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. 2018 Apr 11;8:5847. doi: 10.1038/s41598-018-24207-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differential abundance of KEGG pathways in vegans and omnivores. Orthologous groups were collapsed at pathway level. Pathways within the overall topics of metabolism, environmental information processing, genetic information processing and cellular processes present in ≥10% of individuals were tested for differential abundance in vegans and omnivores using the DESeq2 package. Only metabolic pathways differentially abundant at an FDR ≤ 5% are depicted. Bars indicate mean (standard deviation) proportion of differentially abundant pathways in omnivores. Forest plot indicates log₂ fold difference and corresponding 95% confidence intervals for the difference in pathway abundance between vegans and omnivores. Pathways are coloured by functional category and ordered by decreasing log₂ fold-difference within each category.