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. 2018 Apr 11;8:5802. doi: 10.1038/s41598-018-24223-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pie chart of proteins identified in ND-mucin and grouped according to their predominant areas of expression and/or origin. Most abundant proteins are listed in the figure, with numbers in brackets corresponding to the total number of hits in each group. For protein groups marked with asterisk (*), a full list of candidate proteins is provided in Table S1 (See ESI). Mucus components are designated based on their possible involvement in the formation of mucus granules within the secretory cells and/or their involvement in granule transport (to the membrane) and mucus extrusion process. Blood plasma and cell cytosol components are a broad group of proteins that originate from cytosol components of lysed/sloughed-off epithelial cells as well as blood transudate/blood contamination from the surgical procedure. A small number of identifications are related to digestive enzymes, and proteins involved in nutrient uptake, as well as proteins originating from animal diet (soybean).