Table 1.
N-glycosylated related enzymes identified in global iTRAQ data
| Gene | Protein | Description | Coverage | # Peptides | # PSMs | Gene IDs | LAPC4-WT (115)/LAPC4 -T (114) | LAPC4-AI (116)/LAPC4-WT (114) | LAPC4-AI (117)/LAPC4-WT (114) |
|---|---|---|---|---|---|---|---|---|---|
| DAD1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 | Defender against cell death 1, isoform CRA_a | 26.55 | 3 | 32 | 1603 | 1.310 | 0.986 | 1.030 |
| B4GALT1 | Beta-1,4-galactosyltransferase 1 | Unnamed protein product | 8.14 | 2 | 6 | 2683 | 0.871 | 0.595 | 0.582 |
| MAN2A1 | Alpha-mannosidase 2 | PREDICTED: alpha-mannosidase 2 isoform × 1 | 7.49 | 7 | 18 | 4124 | 1.231 | 0.687 | 0.691 |
| PRKCSH | Glucosidase 2 subunit beta | PRKCSH protein, partial | 13.44 | 7 | 47 | 5589 | 1.092 | 0.768 | 0.743 |
| RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | Unnamed protein product | 53.05 | 27 | 322 | 6184 | 1.226 | 0.910 | 0.901 |
| RPN2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | RPN2 protein, partial | 39.23 | 13 | 107 | 6185 | 1.138 | 0.916 | 0.992 |
| MOGS | Mannosyl-oligosaccharide glucosidase | Mannosyl-oligosaccharide glucosidase isoform 2 | 15.18 | 10 | 37 | 7841 | 1.047 | 0.990 | 0.986 |
| B4GALT3 | Beta-1,4-galactosyltransferase 3 | Unnamed protein product | 12.78 | 3 | 5 | 8703 | 0.794 | 1.262 | 1.131 |
| DPM1 | Dolichol-phosphate mannosyltransferase subunit 1 | Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 24.23 | 5 | 23 | 8813 | 1.227 | 1.031 | 1.161 |
| ALG3 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase | ALG3 protein, partial | 5.08 | 2 | 5 | 10,195 | 1.261 | 0.811 | 0.808 |
| GANAB | GANABGANABNeutral alpha-glucosidase AB | Glucosidase, alpha; neutral AB, isoform CRA_d | 28.3 | 20 | 157 | 23,193 | 1.035 | 1.113 | 1.074 |
| GANAB | GANABGANABNeutral alpha-glucosidase AB | Glucosidase, alpha; neutral AB, isoform CRA_a | 25.73 | 21 | 164 | 23,193 | 1.047 | 1.102 | 1.078 |
| ST8SIA5 | Alpha-2,8-sialyltransferase 8E | Asparagine-linked glycosylation 6 homolog isoform CRA_d | 6.32 | 3 | 5 | 29,929 | 1.118 | 0.776 | 0.793 |
| DPM3 | Dolichol-phosphate mannosyltransferase subunit 3 | Dolichyl-phosphate mannosyltransferase polypeptide 3, isoform CRA_a | 23.91 | 2 | 17 | 54,344 | 1.121 | 0.920 | 0.881 |
| UGGT1 | UDP-glucose:glycoprotein glucosyltransferase 1 | UDP-glucose ceramide glucosyltransferase-like 1 | 10.58 | 17 | 37 | 56,886 | 1.063 | 1.085 | 1.053 |
| ALG8 | Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase | Glucosyltransferase, partial | 4.32 | 2 | 4 | 79,053 | 1.056 | 0.599 | 0.629 |
| ALG2 | Alpha-1,3/1,6-mannosyltransferase ALG2 | Unnamed protein product | 8.06 | 2 | 5 | 85,365 | 1.065 | 2.104 | 2.111 |
| RFT1 | Protein RFT1 homolog | PREDICTED: protein RFT1 homolog isoform × 4 | 13.02 | 6 | 10 | 91,869 | 0.994 | 0.696 | 0.745 |
| STT3B | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B | STT3, subunit of the oligosaccharyltransferase complex, homolog B | 18.04 | 15 | 108 | 2E+05 | 1.163 | 1.031 | 1.029 |
| FUT8 | Alpha-(1,6)-fucosyltransferase | Chain X, crystal structure of human alpha 1,6-fucosyltransferase, Fut8 | 14.26 | 8 | 18 | 2530 | 0.949 | 3.041 | 3.047 |