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. 2018 Apr 11;8:5817. doi: 10.1038/s41598-018-24002-0

Table 2.

SNPs associated with cardiovascular risk factors.

Trait Consortium IVs (n) Unit Sample size (n) Mean age range (years)* Women (% range)** Ancestry R2 (%) F-statistics Pubmed ID
Systolic Blood pressure 74 European cohorts 55 mmHg 201,529 21.5–75.6 0.0–77.2 European 3.4 2588.6 2761845230
Diastolic blood pressure 74 European cohorts 57 mmHg 201,529 21.5–75.6 0.0–77.2 European 3.5 2667.5 2761845230
HDL cholesterol GLGC 89 SD 187,167 21.5–75.0 0.0–69.6 European 1.6 1196.4 2409706831
LDL cholesterol GLGC 80 SD 173,082 21.5–75.0 0.0–69.6 European 2.4 1808.8 2409706831
Triglycerides GLGC 54 SD 177,861 21.5–75.0 0.0–69.6 European 2.1 1578.0 2409706831
Total cholesterol GLGC 88 SD 187,365 21.5–75.0 0.0–69.6 European 2.6 1963.5 2409706831
Fasting glucose MAGIC 35 mmol/L 133,010 11.5–75.7 0.0–71.3 European 4.8 3707.8 2288592432
Fasting Insulin MAGIC 14 Log pmol/L 108,557 11.5–75.7 0.0–71.3 European 1.2 893.9 2288592432
Body mass index GIANT 79 SD 339,224 18.9–75.7 0.0–100.0 European 2.7 2041.1 2567341333
Waist Hip Ratio adjusted Body mass index GIANT 31 SD 224,459 18.9–75.3 0.0–100.0 European 1.4 1044.9 2567341234
Apolipoprotein A-I 14 European cohorts 11 SD 20,687 23.9–60.9 37.0–60.0 European 5.0 3870.4 2700577835
Apolipoprotein B 14 European cohorts 21 SD 20,690 23.9–60.9 37.0–60.0 European 8.6 6918.5 2700577835
Cigarettes smoked per day TAG 1 Cigarettes per day 68,028 39.6–72.3 11.6–100 European 0.5 370.4 2041889036

HDL = High Density Lipoprotein; LDL = Low Density Lipoprotein.

*Range of the mean age of the participants included in the individual studies of the GWAS meta-analysis.

**Range of the percentage of women included in the individual studies of the GWAS meta-analysis.