Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 5;9:348. doi: 10.3389/fphys.2018.00348

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Gu, Liu, Li, Xie, Yao, Zhu, Xu, Dai, Zhong, Zhu, Ding and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Human serum extracellular vesicles inhibit OGD/R induced apoptosis in NRCMs. (A) Western blot for CD63 in supernatant and EVs of human serum (n = 4). (B) Terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) assay for apoptosis in NRCMs treated with OGD/R (n = 4). Scale bar: 100 μm. (C) Analysis for percentage of TUNEL positive cells (n = 4). (D–F) Western blot for Bax, Bcl-2, Caspase 3, and Cleaved caspase 3, and quantitative analysis for Bax/Bcl-2 and Cleaved caspase 3/Caspase 3 ratio. β-actin was used as a loading control (n = 6). **P < 0.01; ***P < 0.001. EVs, extracellular vesicles.