Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Drug susceptibility profile of M. abscessus S strains inactivated in either MAB_4384 (tetR gene) or MAB_4382c (mmpL5 gene).
| MIC (μg/mL) | ||||||
|---|---|---|---|---|---|---|
| Strain | D6 | D15 | D17 | CFZ | BDQ | |
| CIP104536T | 25 | 6.2 | 12.5 | 1.6 | 0.05 | |
| MAB_4384::pUX1 | >200 | >200 | >200 | 1.6 | 0.05 | |
| MAB_4382c::pUX1 | 12.5 | 6.2 | 6.2 | 1.6 | 0.05 | |
The MIC (μg/mL) was determined in CaMH medium. Data are representative of three independent experiments. CFZ, clofazimine; BDQ, bedaquiline.
