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. 2018 Apr 5;9:636. doi: 10.3389/fmicb.2018.00636

Table 1.

Deregulated host miRNAs and lncRNAs in H. pylori infection.

Gene name Type of noncoding gene Variation Associated deregulated genes Type of specimen Associated biological process References
let-7b miRNA down IL-1β, IL-8 Clinical samples Immune response Isomoto et al., 2012
miR-21 miRNA up RECK Clinical samples Cell proliferation, invasion, migration and apoptosis Zhang et al., 2008
miR-103 miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-124 miRNA down SMOX Cell lines DNA damage and tumorigenesis Murray-Stewart et al., 2016
miR-155 miRNA up Tspan14, Lpin1, Pmaip1 and PKIα Clinical samples clinical Immune response and apoptosis Fassi Fehri et al., 2010; Koch et al., 2012
IKK-ε, SMAD2, FADD Samples and cell lines Proinflammatory cytokines Xiao et al., 2009
miR-141 miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-200b miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-200c miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-223 miRNA up NF-kB and ARID1A Clinical samples and cell lines CagA Associated Gastric Carcinogenesis Matsushima et al., 2011; Yang et al., 2018
miR-375 miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-429 miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
miR-532 miRNA down IL-1β, IL-6, IL-8 and TNF-α Clinical samples Immune response Isomoto et al., 2012
lncRNA AF147447 lncRNA down MUC2 Clinical samples Cell proliferation and invasion Zhou et al., 2016
n345630 lncRNA down undefined Clinical samples and cell lines undefined Zhu et al., 2015
XLOC_004787 lncRNA down undefined Clinical samples and cell lines undefined Zhu et al., 2015
n378726 lncRNA down undefined Clinical samples and cell lines undefined Zhu et al., 2015
LINC00473 lncRNA down undefined Clinical samples and cell lines undefined Zhu et al., 2015
XLOC_005517 lncRNA up undefined Cell lines undefined Zhu et al., 2015
LINC00152 lncRNA up undefined Cell lines undefined Zhu et al., 2015
XLOC_13370 lncRNA up undefined Cell lines undefined Zhu et al., 2015
n408024 lncRNA up undefined Cell lines undefined Zhu et al., 2015
XLOC_004122 lncRNA down undefined Clinical samples and cell lines undefined Yang et al., 2015
XLOC_014388 lncRNA down undefined Clinical samples and cell lines undefined Yang et al., 2015
XLOC_004562 lncRNA up undefined Cell lines undefined Yang et al., 2015
XLCO_005912 lncRNA up undefined Cell lines undefined Yang et al., 2015
XLCO_000620 lncRNA up undefined Cell lines undefined Yang et al., 2015