Table 1.
List of the top 50 proteins identified as highly enriched in pseudopodia over cell bodies.
| Gene_symbol | Protein_names | Log 2 ratio | p_values | FDR * _values |
|---|---|---|---|---|
| SLC25A6 | ADP/ATP translocase 3 | 5.40 | 1.53E-05 | 3.51E-04 |
| TBB2 | Tubulin beta-2 chain | 5.05 | 2.87E-07 | 1.93E-04 |
| GOT2 | Aspartate aminotransferase, mitochondrial | 4.97 | 2.46E-05 | 4.25E-04 |
| PHB2 | Prohibitin-2 | 4.58 | 7.21E-05 | 7.15E-04 |
| SLC25A1 | Tricarboxylate transport protein, mitochondrial | 4.50 | 1.48E-04 | 1.05E-03 |
| SLC25A24 | Calcium-binding mitochondrial carrier protein SCaMC-1 | 4.46 | 9.19E-04 | 3.49E-03 |
| ATP5A1 | ATP synthase subunit alpha, mitochondrial | 4.37 | 9.73E-04 | 3.60E-03 |
| ARHGAP1 | Rho GTPase-activating protein 1 | 4.34 | 6.93E-04 | 2.82E-03 |
| TUBB3 | Tubulin beta-3 chain | 4.13 | 1.25E-04 | 9.64E-04 |
| TUBB8 | Tubulin beta-8 chain | 4.05 | 1.12E-04 | 8.94E-04 |
| WDR1 | WD repeat-containing protein 1 | 4.02 | 7.00E-06 | 2.65E-04 |
| GDI2 | Rab GDP dissociation inhibitor beta | 3.97 | 4.86E-06 | 2.55E-04 |
| PHB | Prohibitin | 3.94 | 6.01E-04 | 2.56E-03 |
| Eif3e | Eukaryotic translation initiation factor 3 subunit E | 3.88 | 2.21E-04 | 1.32E-03 |
| CCT7 | T-complex protein 1 subunit eta | 3.84 | 3.90E-05 | 5.02E-04 |
| TUBB | Tubulin beta chain | 3.81 | 6.30E-04 | 2.64E-03 |
| TUBA3 | Tubulin alpha-3 chain;Tubulin alpha-5 chain | 3.81 | 3.38E-03 | 8.70E-03 |
| FH | Fumarate hydratase, mitochondrial | 3.80 | 1.63E-04 | 1.11E-03 |
| EHD4 | EH domain-containing protein 4 | 3.80 | 4.61E-04 | 2.15E-03 |
| ETF1 | Eukaryotic peptide chain release factor subunit 1 | 3.77 | 7.09E-05 | 7.12E-04 |
| UMPS | Uridine 5-monophosphate synthase;Orotate phosphoribosyltransferase | 3.73 | 1.29E-04 | 9.75E-04 |
| SLC25A3 | Phosphate carrier protein, mitochondrial | 3.72 | 2.01E-04 | 1.25E-03 |
| ACTR10 | Actin-related protein 10 | 3.71 | 2.07E-03 | 6.07E-03 |
| TUBB2B | Tubulin beta-2B chain | 3.66 | 2.08E-06 | 2.21E-04 |
| EPHX1 | Epoxide hydrolase 1 | 3.62 | 1.29E-04 | 9.75E-04 |
| NDA3 | Tubulin beta chain | 3.61 | 1.03E-03 | 3.74E-03 |
| SLC16A3 | Monocarboxylate transporter 4 | 3.60 | 1.87E-06 | 2.21E-04 |
| SLC7A5 | Large neutral amino acids transporter small subunit 1 | 3.60 | 1.68E-05 | 3.72E-04 |
| TUBG1 | Tubulin gamma-1 chain;Tubulin gamma-2 chain | 3.56 | 8.38E-04 | 3.25E-03 |
| ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 3.53 | 4.04E-04 | 1.99E-03 |
| PICALM | Phosphatidylinositol-binding clathrin assembly protein | 3.53 | 3.38E-03 | 8.70E-03 |
| ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1 | 3.52 | 1.24E-05 | 3.22E-04 |
| PAICS | Multifunctional protein ADE2 | 3.50 | 1.08E-03 | 3.87E-03 |
| NXN | Nucleoredoxin | 3.48 | 5.29E-05 | 6.02E-04 |
| PSMD12 | 26 S proteasome non-ATPase regulatory subunit 12 | 3.48 | 6.91E-04 | 2.82E-03 |
| SLC3A2 | 4F2 cell-surface antigen heavy chain | 3.47 | 7.52E-05 | 7.34E-04 |
| CORO1C | Coronin-1C | 3.47 | 1.78E-03 | 5.44E-03 |
| OXSR1 | Serine/threonine-protein kinase OSR1 | 3.45 | 1.37E-04 | 1.01E-03 |
| CCT | T-complex protein 1 subunit gamma | 3.45 | 1.25E-06 | 2.21E-04 |
| GPI | Glucose-6-phosphate isomerase | 3.45 | 4.87E-04 | 2.23E-03 |
| ILK1 | Integrin-linked protein kinase1 | 3.45 | 5.62E-04 | 2.44E-03 |
| PSMC3 | 26 S protease regulatory subunit 6 A | 3.44 | 3.42E-05 | 4.84E-04 |
| PNP | Purine nucleoside phosphorylase | 3.42 | 1.83E-05 | 3.84E-04 |
| HSD17B11 | Estradiol 17-beta-dehydrogenase 11 | 3.41 | 1.47E-05 | 3.43E-04 |
| EHD1 | EH domain-containing protein 1 | 3.39 | 1.94E-04 | 1.23E-03 |
| FERMT2 | Fermitin family homolog 2 | 3.38 | 2.29E-03 | 6.45E-03 |
| G6PD | Glucose-6-phosphate 1-dehydrogenase | 3.35 | 3.52E-04 | 1.84E-03 |
| SLC1A5 | Neutral amino acid transporter B | 3.33 | 1.76E-04 | 1.15E-03 |
| CS | Citrate synthase, mitochondrial | 3.33 | 1.91E-03 | 5.76E-03 |
| ASNS | Asparagine synthetase [glutamine-hydrolyzing] | 3.32 | 2.03E-04 | 1.25E-03 |
*FDR: False discovery rate (corrected p-value according to Benjamini-Hochberg1).