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. 2018 Apr 5;12:221. doi: 10.3389/fnins.2018.00221

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Copyright © 2018 Ibayashi, Kunii, Matsuo, Ishishita, Shimada, Kawai and Saito.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrode distribution. The normalized electrode contacts (Red dots) extracted from post-implantation computed tomography from all subjects were overlaid on a normalized brain within FreeSurfer software ver. 6.0.0 (https://surfer.nmr.mgh.harvard.edu/). Note that each set of three electrodes represents one hybrid electrode. Pre-operative MRI was semi-automatically registered to post-operatively scanned computed tomography to determine electrode positions based on a normalized mutual information method using Dr.View (Asahi Kasei, Tokyo, Japan). Both the pre-operative MRI and the registered post-operative computed tomography were then normalized to Montreal Neurological Institute coordinates via linear scale adjustment using SPM8 (http://www.fil.ion.ucl.ac.uk/spm/software/spm8/, Update Revision Number 6313), and then the coordinates for each electrode were extracted.