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Number of mice, number of valid measurements (i.e. IOP, facility, and TM stiffness) and treated eyes in each cohort for DEX study. OD: right eye; OU: both eyes. IOP: intraocular pressure; C: facility; E: TM stiffness.
| Cohort | DEX treatment | Vehicle treatment | Treated eye (s) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Number of mice | IOP | C | E | Number of mice | IOP | C | E | ||
| 1 | 6 | 6 | 0 | 6 | 3 | 3 | 0 | 3 | OD |
| 2 | 4 | 4 | 0 | 4 | 0 | 0 | 0 | 0 | OD |
| 3 | 6 | 6 | 2 | 6 | 5 | 5 | 3 | 5 | OU |
| 4 | 5 | 5 | 5 | 5 | 4 | 4 | 4 | 4 | OU |
| 5 | 4 | 4 | 4 | 4 | 4 | 4 | 3 | 4 | OU |
| Total | 25 | 25 | 11 | 25 | 16 | 16 | 10 | 16 | |
