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. 2018 Mar 30;38(4):348–354. doi: 10.3343/alm.2018.38.4.348

Table 3. Univariate and multivariate analyses for predicting liver fibrosis stage ≥2 and 3.

P Univariate P Multivariate
Odds ratio 95% CI Odds ratio 95% CI
Fibrosis stage ≥ 2
 WFA-M2BP < 0.001 5.182 2.096–12.81 0.050 3.790 1.005–14.46
 ELF < 0.001 2.109 1.479–3.008 0.030 1.994 1.071–3.714
 Fibroscan 0.031 1.102 1.009–1.204 NS
 FIB-4 0.042 4.574 1.053–19.86 NS
 APRI 0.044 1.594 1.012–2.510 NS
 Albumin NS NS
 ALT NS NS
 AST NS NS
 Hemoglobin NS NS
 Prothrombin Time 0.001 2.618 1.452–4.718 NS
 Platelet < 0.001 0.986 0.978–0.994 0.023 0.987 0.976–0.998
 HBsAg NS NS
Fibrosis stage 3
 WFA-M2BP 0.01 1.784 1.152–2.764 NS
 ELF score 0.018 1.616 1.085–2.406 NS
 Fibroscan 0.006 1.095 1.026–1.168 NS
 FIB-4 NS NS
 APRI NS NS
 Albumin NS NS
 ALT NS NS
 AST NS NS
 Hemoglobin NS NS
 Prothrombin Time 0.049 1.207 1.001–1.455 NS
 Platelet 0.011 0.982 0.968–0.996 0.037 0.502 0.117–2.160
 HBsAg NS NS

Abbreviations: CI, confidence interval; WFA-M2BP, Wisteria floribunda agglutinin-positive Mac-2 binding protein; APRI, AST-to-platelet ratio; ELF, enhanced liver fibrosis; HBsAg, hepatitis B surface antigen; NS, not significant.