Table 3. Univariate and multivariate analyses for predicting liver fibrosis stage ≥2 and 3.
P | Univariate | P | Multivariate | |||
---|---|---|---|---|---|---|
Odds ratio | 95% CI | Odds ratio | 95% CI | |||
Fibrosis stage ≥ 2 | ||||||
WFA-M2BP | < 0.001 | 5.182 | 2.096–12.81 | 0.050 | 3.790 | 1.005–14.46 |
ELF | < 0.001 | 2.109 | 1.479–3.008 | 0.030 | 1.994 | 1.071–3.714 |
Fibroscan | 0.031 | 1.102 | 1.009–1.204 | NS | ||
FIB-4 | 0.042 | 4.574 | 1.053–19.86 | NS | ||
APRI | 0.044 | 1.594 | 1.012–2.510 | NS | ||
Albumin | NS | NS | ||||
ALT | NS | NS | ||||
AST | NS | NS | ||||
Hemoglobin | NS | NS | ||||
Prothrombin Time | 0.001 | 2.618 | 1.452–4.718 | NS | ||
Platelet | < 0.001 | 0.986 | 0.978–0.994 | 0.023 | 0.987 | 0.976–0.998 |
HBsAg | NS | NS | ||||
Fibrosis stage 3 | ||||||
WFA-M2BP | 0.01 | 1.784 | 1.152–2.764 | NS | ||
ELF score | 0.018 | 1.616 | 1.085–2.406 | NS | ||
Fibroscan | 0.006 | 1.095 | 1.026–1.168 | NS | ||
FIB-4 | NS | NS | ||||
APRI | NS | NS | ||||
Albumin | NS | NS | ||||
ALT | NS | NS | ||||
AST | NS | NS | ||||
Hemoglobin | NS | NS | ||||
Prothrombin Time | 0.049 | 1.207 | 1.001–1.455 | NS | ||
Platelet | 0.011 | 0.982 | 0.968–0.996 | 0.037 | 0.502 | 0.117–2.160 |
HBsAg | NS | NS |
Abbreviations: CI, confidence interval; WFA-M2BP, Wisteria floribunda agglutinin-positive Mac-2 binding protein; APRI, AST-to-platelet ratio; ELF, enhanced liver fibrosis; HBsAg, hepatitis B surface antigen; NS, not significant.