Table 4.
Summary of the effects of dog and owner OXTR polymorphisms on dogs' Attachment, Anxiety, and Acceptance composite scores as measured in the Strange Situation Test.
| Composite score | Effect | WCS | p | Detail |
|---|---|---|---|---|
| Attachment | Main effects | |||
| −213AG | 20.735 | <0.01 | AA+AG > GG | |
| −94TC | 0.458 | >0.1 | ||
| −74CG | 16.086 | <0.01 | CC+CG > GG | |
| rs1042778 | 11.573 | <0.01 | CC > AA+AC | |
| rs2254298 | 14.190 | <0.01 | CT+TT > CC | |
| rs53576 | 0.000 | >0.1 | ||
| Country | 1.887 | >0.1 | ||
| Significant pairwise interactions | ||||
| −213AG × rs2254298 | 12.340 | <0.01 | AA+AG (−213AG) +CC (rs2254298) > GG (−213AG) + CC (rs2254298) | |
| −213AG × rs53576 | 7.772 | <0.05 | AA+AG (−213AG) + CT+TT (rs53576) > GG (−213AG) + CT+TT (rs53576) | |
| −74CG × rs53576 | 10.904 | <0.01 | GG (−74CG) + CT+TT (rs53576) > CC+CG (−74CG) + CT+TT (rs53576) | |
| Country × −213AG | 15.817 | <0.01 | Austria AA+AG > Austria GG | |
| Country × −74CG | 24.791 | <0.01 | Hungary GG > Austria GG | |
| Anxiety | Main effects | |||
| −213AG | 4.868 | >0.1 | ||
| −94TC | 0.000 | >0.1 | ||
| −74CG | 7.808 | <0.05 | CC+CG > GG | |
| rs1042778 | 1.988 | >0.1 | ||
| rs2254298 | 1.369 | >0.1 | ||
| rs53576 | 1.222 | >0.1 | ||
| Country | 3.954 | |||
| Significant pairwise interactions | ||||
| −213AG × rs53576 | 14.826 | <0.01 | AA+AG (−213AG) + CT+TT (s53576) > AA+AG (−213AG) + CC (rs53576) | |
| −74CG × rs53576 | 5.955 | <0.05 | GG (−74CG) + CT+TT (rs53576) > CC+CG (−74CG) + CT+TT (rs53576) | |
| Country × −213AG | 20.088 | <0.01 | Austria AA+AG > Austria GG | |
| Country × −74TC | 10.421 | <0.01 | Hungary GG > Austria GG | |
| Acceptance | Main effects | |||
| −213AG | 4.562 | >0.1 | ||
| −94TC | 0.101 | >0.1 | ||
| −74CG | 6.233 | <0.05 | CC+CG > GG | |
| rs1042778 | 0.548 | >0.1 | ||
| rs2254298 | 1.480 | >0.1 | ||
| rs53576 | 6.331 | <0.05 | CT+TT > CC | |
| Country | 1.592 | >0.1 | ||
| Significant pairwise interactions | ||||
| −213AG × rs1042778 | 13.561 | <0.01 | GG (−213AG) + CT+TT (rs53576) > GG (−213AG) + CC (rs53576) | |
| −213AG × rs53576 | 12.347 | <0.01 | CC (−94TC) + CT+TT (rs53576) > CT+TT (−94TC) + CT+TT (rs53576) | |
| −94TC × rs1042778 | 12.695 | <0.01 | CT+TT (−94TC) + CC (rs1042778) > CC (−94TC) + CC (rs1042778) | |
| −74CG × rs1042778 | 12.018 | <0.01 | CC+CG (−74CG) + AA+AC (rs1042778) > GG (−74CG) + AA+AC (rs1042778) | |
| −74CG × rs53576 | 16.541 | <0.01 | CC+CG (−74CG) + CT+TT (rs53576) > GG (−74CG) + CT+TT (rs53576) | |
Significant effects are highlighted in bold.