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. 2018 Feb;15(2):123–130. doi: 10.11909/j.issn.1671-5411.2018.02.001

Table 3. Multi-variate predictors of in-hospital mortality for nonagenarian hospitalizations with transcatheter aortic valve replacement (n = 6005).

Variable name Odds ratio (95% CI) P
*Age 1.08 (1.05–1.10) < 0.01
Female vs. Male 1.58 (1.38–1.81) < 0.01
Admission type
 Non-elective vs. elective 1.02 (0.89–1.18) 0.75
Primary payer
 Medicare Referent
 Medicaid 1.31 (0.48–3.55) 0.59
 Private insurance (Including HMOs and PPOs) 1.23 (0.86–1.76) 0.26
 Self-pay/other 0.48 (0.19–1.23) 0.13
Median household income for patient's ZIP code
 0–25 Percentile Referent
 26–50 Percentile 1.02 (0.83–1.25) 0.86
 51–75 Percentile 0.98 (0.80–1.19) 0.81
 76–100 Percentile 1.33 (1.10–1.59) < 0.01
Teaching status of hospital
 Rural Referent
 Urban (Non-teaching) 0.67 (0.34–1.32) 0.25
 Urban (Teaching) 0.54 (0.28–1.05) 0.07
**Comorbidities
 Diabetes mellitus (uncomplicated) 0.67 (0.56–0.80) < 0.01
 Diabetes mellitus (with chronic complications) 1.07 (0.79–1.44) 0.67
 Hypertension 0.45 (0.39–0.52) < 0.01
 Liver disease 1.45 (0.86–2.44) 0.17
 Fluid and electrolytes disorder 1.98 (1.73–2.27) < 0.01
 Neurological disorder 0.88 (0.67–1.14) 0.33
 Obesity 0.87 (0.66–1.15) 0.32
 Peripheral vascular disease 1.25 (1.09–1.44) < 0.01
 Smoking 0.77 (0.44–1.36) 0.37
 Alcohol 1.14 (0.46–2.84) 0.78
 Prior MI 0.94 (0.75–1.16) 0.55
 Coagulopathy 1.28 (1.11–1.48) < 0.01
 Chronic pulmonary disease 1.41 (1.22–1.62) < 0.01
 Congestive heart failure 0.95 (0.79–1.16) 0.63
 Ischemic cardiomyopathy 0.55 (0.40–0.77) < 0.01
 Mitral stenosis 2.80 (1.91–4.11) < 0.01
 Mitral insufficiency 1.34 (1.15–1.56) < 0.01
 Chronic kidney disease 1.19 (1.04–1.37) 0.01
 Composite of hemo and peritoneal dialysis 4.85 (3.88–6.04) < 0.01
Procedural details
 **IABP 11.78 (9.25–15.00) < 0.01
 pLVAD or ECMO 21.34 (14.0–32.55) < 0.01
#Trans-apical approach 0.97 (0.83–1.14) 0.76

*Age is a continuous variable; **Reference group was not available; #Transfemoral approach was taken as a reference. ECMO: extracorporeal membrane oxygenation; HMOs: health maintenance organizations; IABP: intra-aortic balloon pump; MI: myocardial infarction; pLVAD: percutaneous left ventricular assist device; PPOs: preferred provider organizations.