Table 3. Multi-variate predictors of in-hospital mortality for nonagenarian hospitalizations with transcatheter aortic valve replacement (n = 6005).
Variable name | Odds ratio (95% CI) | P |
*Age | 1.08 (1.05–1.10) | < 0.01 |
Female vs. Male | 1.58 (1.38–1.81) | < 0.01 |
Admission type | ||
Non-elective vs. elective | 1.02 (0.89–1.18) | 0.75 |
Primary payer | ||
Medicare | Referent | |
Medicaid | 1.31 (0.48–3.55) | 0.59 |
Private insurance (Including HMOs and PPOs) | 1.23 (0.86–1.76) | 0.26 |
Self-pay/other | 0.48 (0.19–1.23) | 0.13 |
Median household income for patient's ZIP code | ||
0–25 Percentile | Referent | |
26–50 Percentile | 1.02 (0.83–1.25) | 0.86 |
51–75 Percentile | 0.98 (0.80–1.19) | 0.81 |
76–100 Percentile | 1.33 (1.10–1.59) | < 0.01 |
Teaching status of hospital | ||
Rural | Referent | |
Urban (Non-teaching) | 0.67 (0.34–1.32) | 0.25 |
Urban (Teaching) | 0.54 (0.28–1.05) | 0.07 |
**Comorbidities | ||
Diabetes mellitus (uncomplicated) | 0.67 (0.56–0.80) | < 0.01 |
Diabetes mellitus (with chronic complications) | 1.07 (0.79–1.44) | 0.67 |
Hypertension | 0.45 (0.39–0.52) | < 0.01 |
Liver disease | 1.45 (0.86–2.44) | 0.17 |
Fluid and electrolytes disorder | 1.98 (1.73–2.27) | < 0.01 |
Neurological disorder | 0.88 (0.67–1.14) | 0.33 |
Obesity | 0.87 (0.66–1.15) | 0.32 |
Peripheral vascular disease | 1.25 (1.09–1.44) | < 0.01 |
Smoking | 0.77 (0.44–1.36) | 0.37 |
Alcohol | 1.14 (0.46–2.84) | 0.78 |
Prior MI | 0.94 (0.75–1.16) | 0.55 |
Coagulopathy | 1.28 (1.11–1.48) | < 0.01 |
Chronic pulmonary disease | 1.41 (1.22–1.62) | < 0.01 |
Congestive heart failure | 0.95 (0.79–1.16) | 0.63 |
Ischemic cardiomyopathy | 0.55 (0.40–0.77) | < 0.01 |
Mitral stenosis | 2.80 (1.91–4.11) | < 0.01 |
Mitral insufficiency | 1.34 (1.15–1.56) | < 0.01 |
Chronic kidney disease | 1.19 (1.04–1.37) | 0.01 |
Composite of hemo and peritoneal dialysis | 4.85 (3.88–6.04) | < 0.01 |
Procedural details | ||
**IABP | 11.78 (9.25–15.00) | < 0.01 |
pLVAD or ECMO | 21.34 (14.0–32.55) | < 0.01 |
#Trans-apical approach | 0.97 (0.83–1.14) | 0.76 |
*Age is a continuous variable; **Reference group was not available; #Transfemoral approach was taken as a reference. ECMO: extracorporeal membrane oxygenation; HMOs: health maintenance organizations; IABP: intra-aortic balloon pump; MI: myocardial infarction; pLVAD: percutaneous left ventricular assist device; PPOs: preferred provider organizations.