Table 3. ISR risk factors.

Patient's factors	Lesion's factors	Peri-procedural risk factors
Diabetes mellitus	Complex B2/C lesions	Sub-optimal apposition
Renal insufficiency	Long lesions > 20 mm	Under-expansion of the stent
Acute coronary syndromes	Artery diameter < 3 mm	Post-PCI MLD < 3 mm
	Chronic closures	Implantation of multiple
	Ostial lesions	Stents
	Bifurcation lesions	Stent fractures
	Lesions in venous bypass recurrent restenosis	Type of stent

ISR: in-stent restenosis; MLD: minimal lumen diamether; PCI: percutaneous coronary angioplasty.