Table 1.

Prevalence of ophthalmic findings in the 23 patients with Wolfram syndrome

Study parameter	Percentage patients affected
Visual acuity <0.3 logMAR	96 (22/23)
RNFL thinning ≤80 μ	100 (23/23)
Visual field reduced sensitivity and/or scotoma	100 (23/23)
Dyschromatopsia	96 (22/23)
Optic nerve pallor	96 (22/23)
Optic nerve cup:disc ratio ≥0.4	39 (9/23)
Afferent pupillary defect	65 (15/23)
Nystagmus	43 (10/23)
Strabismus	43 (10/23)
Cataract	22 (5/23)

logMAR, log minimum angle resolution; RNFL, retinal nerve fibre layer.