Figure 2. Investigation of intracellular trafficking mechanism of tandem peptide nanoparticles.
Flow cytometric analysis of Neuro-2a cells incubated with fluorescently labeled nanoparticles at (A) 4 °C and (B) 37 °C. (C) Knockdown activity of nanoparticles in the presence of chloroquine analyzed by RT-qPCR. There was no statistical difference between knockdown with or without chloroquine at matched peptide:siRNA ratios as determined by analysis with One-way ANOVA.