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. 2018 Apr 11;10:51. doi: 10.1186/s13148-018-0479-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Q-Q plots of the 22 p values for the 5-year OS analysis. Under the null hypothesis of no association, p values follow a uniform distribution between 0 and 1. The diagonal line shows this expected distribution of p values. The points on the plot show the p values observed in the survival analysis. For all breast adenocarcinomas together (panel a) and only the ductal adenocarcinomas (panel b), the presence of many points above the diagonal line indicates a substantial enrichment in low p values. The p values in the lobular subset (panel c) are closely following the expected distribution of the p values, indicating no enrichment in low p values there