Table 1.

Results using our method to validate existing potential drug target predicted computationally [18].

S/N	Reaction	EC number	Yeh et al. [17]	Fatumo et al. [47]	Huthmacher et al. [5]	Plata et al. [8]	Bazzani et al. [70]	Chiappino-Pepe et al. [9]	This study
(1)	DIHYDROFOLATEREDUCT-RXN	1.5.1.3	Yes	Yes	Yes	Yes	Yes	Yes	Yes
(2)	THYMIDYLATESYN-RXN	2.1.1.45	Yes	Yes	Yes	Yes	Yes	Yes	Yes
(3)	H2PTEROATESYNTH-RXN	2.5.1.15	Yes	Yes	Yes	Yes	No	No	Yes
(4)	IMP-DEHYDROG-RXN	1.1.1.205	Yes	Yes	Yes	No	Yes	No	Yes
(5)	SUPEROX-DISMUT-RXN	1.15.1.1	Yes	Yes	Yes	No	Yes	No	Yes
(6)	ADENOSYLHOMOCYSTEINASE-RXN	3.3.11	Yes	Yes	Yes	No	Yes	No	Yes
(7)	OROTPDECARB-RXN	4.1.1.23	Yes	Yes	Yes	Yes	Yes	Yes	Yes
(8)	SAMDECARB-RXN	4.1.1.50	Yes	Yes	Yes	Yes	Yes	No	Yes
(9)	PORPHOBILSYNTH-RXN	4.2.1.24	Yes	Yes	Yes	Yes	Yes	No	Yes
(10)	GLUTCYSLIG-RXN	6.3.2.2	Yes	Yes	Yes	No	Yes	No	Yes