Table 2.
The top seven predicted most essential reactions from this study.
| S/N | Reaction | Gene ID | Common name | EC number | Number of affected reactions | Essentiality |
|---|---|---|---|---|---|---|
| (1) | SUPEROX-DISMUT-RXN | PFF1130C, PF08_0071 | Superoxide dismutase | 1.15.1.1 | 94 | 1.27027027 |
| (2) | CATAL-RXN | Catalase | 1.11.1.6 | 74 | 1 | |
| (3) | S-ADENMETSYN-RXN | PFI1090W | Methionine adenosyltransferase | 2.5.1.6 | 49 | 0.662162162 |
| (4) | 2.5.1.19-RXN | 3-Phosphoshikimate 1-carboxyvinyltransferase | 2.5.1.19 | 48 | 0.648648649 | |
| (5) | CHORISMATE-SYNTHASE-RXN | PFF1105C | 5-O-(1-Carboxyvinyl)-3-phosphoshikimate phosphate-lyase | 4.2.3.5 | 48 | 0.648648649 |
| (6) | SHIKIMATE-KINASE-RXN | Shikimate kinase | 2.7.1.71 | 48 | 0.648648649 | |
| (7) | ADENOSYLHOMOCYSTEINASE-RXN | PFE1050W | Adenosylhomocysteinase | 3.3.1.1 | 39 | 0.527027027 |