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. 2018 Jan 23;2018:4565630. doi: 10.1155/2018/4565630

Figure 1.

Figure 1

Experimental protocols. Mice were randomly assigned into five groups: (a) sham group (mice underwent sham surgery); (b) I/R group (mice underwent 40 min left anterior descending artery occlusion, followed by 120 min reperfusion); (c) RIPostC group (mice were underwent ischemic reperfusion injury, where remote conditioning was applied at the beginning of cardiac reperfusion). (d) RIPostC + Ly group (mice were injected with the PI3K inhibitor LY294002 and then underwent ischemic reperfusion injury, where remote conditioning was applied at the beginning of cardiac reperfusion). I/R: ischemia/reperfusion; RIPostC: remote ischemic postconditioning.