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. Author manuscript; available in PMC: 2019 Feb 20.
Published in final edited form as: Circulation. 2018 Feb 20;137(8):771–780. doi: 10.1161/CIRCULATIONAHA.117.030526

Table 3.

Clinical Event Rate and Hazard Ratio for Women versus Men

Clinical Event Women (N=148) Men (N=1064) Model Hazard Ratio (95% CI) P-value
N (%) of Events 10-Year KM Rate* (%) (95% CI) Event Rate per person- year N (%) of Events 10-Year KM Rate* (%) (95% CI) Event Rate per person- year
All-cause Mortality 73 (49.3) 49.0 (40.8, 57.3) 0.073 684 (64.3) 65.8 (62.7, 68.8) 0.105 Unadjusted 0.70 (0.55, 0.89) 0.003
Adjusted† 0.67 (0.52, 0.86) 0.002
Cardiovascular Mortality 48 (32.4) 34.3 (26.3, 42.3) 0.048 496 (46.6) 52.3 (48.9, 55.8) 0.076 Unadjusted 0.64 (0.48, 0.86) 0.003
Adjusted† 0.65 (0.48, 0.89) 0.006
Mortality or Cardiovascular Hospitalization 112 (75.7) 76.6 (68.5, 84.6) 0.111 879 (82.6) 85.2 (82.2, 88.2) 0.135 Unadjusted 0.87 (0.72, 1.06) 0.180
Adjusted† 0.86 (0.70, 1.05) 0.144
Sudden Cardiac Death 21 (14.2) 17.6 (10.7, 24.5) 0.021 249 (23.4) 30.2 (26.8, 33.7) 0.038 Unadjusted 0.56 (0.36, 0.87) 0.011
Adjusted† 0.62 (0.39, 0.97) 0.038
Heart Failure Death 10 (6.8) 7.5 (2.7, 12.3) 0.010 148 (13.9) 21.9 (18.5, 25.4) 0.023 Unadjusted 0.44 (0.23, 0.83) 0.012
Adjusted† 0.40 (0.21, 0.77) 0.007
*

10-year KM Rate=Kaplan-Meier estimates of event rate at 10 years after randomization.

†

The adjustment variables include treatment, age, race, HF class at baseline, history of MI, previous revascularization, number of diseased vessels, baseline ejection fraction, chronic renal insufficiency, history of atrial flutter/fibrillation, mitral regurgitation, history of stroke, hemoglobin and hyperlipidemia.