Table 2. Preoperative disease characteristics and operative outcomes.
| Category | UAB | Baptist Health of South Florida | IEO | MSKCC | Overall |
|---|---|---|---|---|---|
| Patients, n | 438 | 319 | 154 | 428 | 1339 |
|
| |||||
| Primary tumor location, % | |||||
| RUL | 40 | 32 | 37 | 38 | 37 |
| RML | 8 | 8 | 8 | 6 | 7 |
| RLL | 18 | 17 | 14 | 20 | 18 |
| LUL | 16 | 26 | 25 | 21 | 21 |
| LLL | 16 | 14 | 16 | 14 | 15 |
| Others | 2 | 3 | 0 | 1 | 2 |
|
| |||||
| Histology, % | |||||
| Adenocarcinoma | 60 | 60 | 81 | 80 | 69 |
| Squamous cell carcinoma | 27 | 18 | 12 | 10 | 18 |
| Other | 13 | 22 | 7 | 10 | 14 |
|
| |||||
| Pathologic stage, %* | |||||
| IA | 49 | 47 | 56 | 52 | 50 |
| IB | 20 | 24 | 23 | 19 | 21 |
| IIA | 9 | 6 | 6 | 11 | 8 |
| IIB | 9 | 11 | 3 | 5 | 8 |
| IIIA | 10 | 11 | 9 | 12 | 11 |
| IIIB | 1 | 1 | 0 | 0 | 1 |
| IV | 2 | 0 | 3 | 1 | 1 |
|
| |||||
| Tumor size, mm, median (range) | 30 (4-188) | 22 (4-250) | 19 (2-80) | 21 (1-200) | 21 (2-250) |
|
| |||||
| No. of N1, N2 lymph node stations, median (range) | 8 (7-10) | 6 (4-9) | N/A | 5 (4-9) | 6 (4-10) |
|
| |||||
| No. of N1, N2 lymph nodes, median (range) | 19 (11-42) | 10 (5-40) | 15 (7-35) | 16 (7-48) | 13 (0548) |
|
| |||||
| Operative time, min, median (range) | 129 (43-348) | 133 (40-300) | 195 (93-411) | 182 (38-394) | 136 (38-411) |
|
| |||||
| Estimated blood loss, mL, median (range) | 20 (10-800) | 75 (20-1000) | N/A | N/A | 50 (10-1000) |
|
| |||||
| Blood transfusion, n | 1 | 3 | N/A | N/A | 4 |
|
| |||||
| Conversion to thoracotomy, total, n (%) | 41 (9) | 12 (4) | 18 (12) | 45 (11) | 116 (9) |
|
| |||||
| Bleeding, n (%) | 13 (3) | 3 (1) | 4 (3) | 4 (1) | 24 (2) |
|
| |||||
| Length of stay, d, median (range)† | 3 (1-41) | 3 (1-86) | 5 (3-73) | 4 (1-35) | 3 (1-86) |
|
| |||||
| Complications, % | |||||
| None | 84 | 74 | 71 | 72 | 76 |
| Minor | 10 | 19 | 25 | 18 | 16 |
| Major | 6 | 8 | 4 | 10 | 8 |
In this study, stage IIIA included a highly selected group of patients who had a single station N2 disease. Stage IIIB included 8 patients who were clinically staged as T4N2 who had multiple pulmonary nodules found in different ipsilateral lung lobes. Stage IV included 18 patients with multiple nodules found in the contralateral chest who had no concurrent nodal disease and which could have been separate primaries. UAB, University of Alabama at Birmingham; IEO, Istituto Europeo Di Oncologia; MSKCC, Memorial Sloan Kettering Cancer Center; RUL, right upper lob; RML, right middle lobe; RLL, right lower lobe; LUL, left upper lobe; LLL, left lower lobe; N/A, not available.
According to the American Joint Committee on Cancer (Seventh Edition): Lung Cancer Staging.
Length of stay considers any hospital stay less than 24 hours as 1 day.