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. 2018 May;46(5):619–627. doi: 10.1124/dmd.117.079228

TABLE 5.

Univariate associations between SNPs and BCRP protein expression

SNPa,b Regression Parameter Estimate for Additive Effect on BCRP Protein Expression S.E. of Parameter Estimate for Additive Effect on BCRP Protein Expression t-Statistic for SNP Effect on BCRP Protein Expression P Value for SNP Effect on BCRP Protein Expression Bonferroni-Adjusted P Value for SNP Effect on BCRP Protein Expression
C46847T 0.0247 0.0169 1.46 0.149 1.000
G46932C −0.0023 0.0256 −0.09 0.928 1.000
G59582A 0.0213 0.0178 1.20 0.235 1.000
A61562C 0.0097 0.0326 0.30 0.767 1.000
C61785T 0.0120 0.0215 0.56 0.578 1.000
C72144T −0.0279 0.0148 −1.88 0.065 1.000
T73809C −0.0210 0.0147 −1.42 0.159 1.000
C78551T 0.0227 0.0227 1.220 0.227 1.000
A92873G 0.0142 0.0158 0.90 0.373 1.000
A92894C 0.0207 0.0151 0.137 0.175 1.000
T93490C 0.0102 0.0180 0.57 0.574 1.000
C93624A −0.0294 0.0154 −1.91 0.060 1.000
G94112A 0.0104 0.225 0.46 0.646 1.000
A96567G 0.0008 0.0274 0.03 0.976 1.000
C421Ac −0.0666 0.0195 −3.42 0.001 0.018
T141300C 0.0097 0.0184 0.53 0.598 1.000
A141618G −0.0227 0.0147 −1.54 0.127 1.000
a

AC084732 (first nucleotide of gene = 1).

b

SNPS G34A, C369T, and C376T were removed from analysis due to small sample size.

c

Starting at translational start site (+1) and excluding nucleotides in the noncoding region.