Table 2.
Performance of VIDAS GDH and VIDAS CDAB detection for diagnosis of CDI
| Test methods | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) |
|---|---|---|---|---|
| GDHa | 98.8 (92.7–99.9) | 92.6 (89.6–94.8) | 73.0 (63.8–80.7) | 99.7 (98.3–100.0) |
| CDABb | 54.2 (42.1–65.8) | 100.0 (98.9–100.0) | 100.0 (88.8–100.0) | 92.9 (90.1–95.0) |
Notes:
a
Compare to culture;
b
Compare to toxigenic culture.
Abbreviations: GDH, glutamate dehydrogenase; CDAB, C. difficile toxin A&B; PPV, positive predictive value; NPV, negative predictive value.