Table 2.
Serum biochemical parameters of T2DM patients maintained on Met and treated with GKB extract
| Parameters | Met+placebo, n=20
|
Met+GKB, n=27
|
||
|---|---|---|---|---|
| Baseline | 90 days | Baseline | 90 days | |
| AST (U/L) | 22.2±13.5 | 18.1±5.4 | 18.4±6.6 | 18.8±4.4 |
| ALT (U/L) | 19.2±8.7 | 17.0±7.3 | 17.8±8.9 | 17.5±7.4 |
| ALP (U/L) | 97.6±27.0 | 82.1±22.8* | 93.8±20.6 | 86.1±15.6* |
| Urea (mg/dL) | 25.6±7.5 | 27.1±10.6 | 28.1±6.3 | 24.5±6.9* |
| Creatinine (mg/dL) | 0.67±0.17 | 0.73±0.14* | 0.69±0.17 | 0.60±0.16* |
Notes: Values are presented as mean±SD.
*
For each treatment group, mean is significantly different from the baseline value (paired t-test, P<0.05).
Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GKB, Ginkgo biloba; Met, metformin; T2DM, type 2 diabetes mellitus.