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. 2018 Apr 5;13:2079–2091. doi: 10.2147/IJN.S153701

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© 2018 Brueckner et al. This work is published by Dove Medical Press Limited, and licensed under a Creative Commons Attribution License

The full terms of the License are available at http://creativecommons.org/licenses/by/4.0/. The license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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PIXE analysis of PEMPs and PEMCs to detect free Ca after CaCO₃ core dissolution.

Notes: The Ca-maps are shown in A1 (PEMPs) and B1 (PEMCs), whereas the S-maps are shown in A2 (PEMPs) and B2 (PEMCs). PEMP Ca profile lines and Ca outlines (amount) were taken directly from the Ca map, whereas PEMCs were located using S-map, and profile lines and outlines were translated into the Ca map. Representative Ca-profiles (C) of PEMPs (black) and PEMCs (red) indicate the complete CaCO₃ removal during core dissolution, which is verified by the relative Ca content (D). Scale bars: 10 µm.

Abbreviations: CaCO₃, calcium carbonate; PEMC, polyelectrolyte-coated microcapsule; PEMP, polyelectrolyte-coated microparticle; PIXE, proton-induced X-ray emission; Rel, relative.