Table 3.
Moderator | Number of association studies | Meta-regression analysis
|
Heterogeneity
|
||||
---|---|---|---|---|---|---|---|
Slope | 95% CI lower | 95% CI upper | p-value | l2 (%) | Q (p-value) | ||
Age (mean year) | 10 | 0.0078 | −0.027 | 0.042 | 0.66 | 82.3 | <1.0×10−4 |
Gender (% male) | 11 | 0.0006 | −0.018 | 0.019 | 0.95 | 79.7 | <1.0×10−4 |
Medication exposure (% medication-received patients) | 10 | −0.0018 | −0.012 | 0.0083 | 0.73 | 74.8 | 1.2×10−4 |
Sample size | 12 | −0.0012 | −0.0041 | 0.0017 | 0.42 | 72.2 | 2.4×10−4 |
Published year | 12 | −0.0018 | −0.035 | 0.032 | 0.92 | 77.3 | <1.0×10−4 |
Abbreviation: MDD, major depressive disorder.