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Drug efficiency and drug-loading capacity of NQ freebase PLGA 502, PLGA 502H, PLGA 503, and PLGA 503H microspheres
| Property | NQ freebase PLGA 502 MSs | NQ freebase PLGA 502H MSs | NQ freebase PLGA 503 MSs | NQ freebase PLGA 503H MSs |
|---|---|---|---|---|
| Efficiency (%) | 30.33±0.51 | 46.19±0.33 | 32.69±1.28 | 48.30±3.04 |
| Drug-loading capacity (%) | 5.0±0.08 | 7.4±0.06 | 5.48±0.19 | 8.21±0.52 |
Abbreviations: NQ, N-desalkyl quetiapine; MSs, microspheres; PLGA, poly(d,l-lactic-co-glycolic acid).
