Table 3.
Multivariate linear regression analysis for morphine equivalent (mg) in POD 0–2 after VATS lung lobectomy
| Variables | Multivariate Model 1
|
Multivariate Model 2
|
||
|---|---|---|---|---|
| Coefficient (95% CI) | P-value | Coefficient (95% CI) | P-value | |
| Sex | ||||
| Female (vs male) | 4.07 (−48.93, 109.18) | 0.455 | ||
| ASA class | ||||
| 1 (vs 2–3) | 10.33 (−9.21, 29.87) | 0.751 | ||
| Preoperative diabetes mellitus | 20.76 (−3.42, 44.95) | 0.092 | 18.23 (−5.16, 41.62) | 0.127 |
| Preoperative psychiatric disorder | −37.83 (−122.63, 46.97) | 0.382 | ||
| Surgery time (min) | 0.55 (0.40, 0.69) | <0.001 | 0.53 (0.39, 0.68) | <0.001 |
| Postoperative ICU admission | 10.74 (−60.68, 42.16) | 0.503 | ||
| Never smoker (vs non-never smoker) | −25.19 (−52.17, 1.80) | 0.067 | −17.48 (−33.83, −1.13) | 0.036 |
| Total smoking amount (packs) | −0.001 (−0.002, 0.001) | 0.327 | ||
Notes: Multivariate Model 1: eight variables with P value <0.2 from the univariate model were included in the multivariable Model 1. Multivariate Model 2: backward variable selection method with an elimination criterion of 0.1 was performed to fit the multivariable model.
Abbreviations: ASA, American Society of Anesthesiologists; ICU, intensive care unit; POD, postoperative day; VATS, video-assisted thoracic surgery.