Table 2.
Bivariate Analysis of Fatigue and Hemoglobin Measures
| Hemoglobin Measure | Range | Full Population (N=784) | Excluding SC/GIB Patients (N=666) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||
| Subjects (n=784) |
Mean Fatigue Score* (s.e) |
P** | % High Fatigue, FACIT<27 | P*** | Subjects (n=594) |
Mean Fatigue Score* (s.e) |
P** | % High Fatigue, FACIT<27 | P*** | ||
| Mean | Hb<8g/dL | 214 | 26 (1.0) | 0.07 | 47 | 0.05 | 147 | 25 (1.2) | 0.06 | 51 | 0.09 |
| 8g/dL≤Hb<9g/dL | 370 | 25 (0.7) | 53 | 283 | 25 (0.8) | 53 | |||||
| Hb≥9g/dL | 200 | 28 (1.0) | 43 | 164 | 28 (1.1) | 43 | |||||
|
| |||||||||||
| Median | Hb<8g/dL | 222 | 26 (1.0) | 0.47 | 48 | 0.65 | 157 | 24 (1.1) | 0.3 | 52 | 0.81 |
| 8g/dL≤Hb<9g/dL | 380 | 26 (0.7) | 50 | 291 | 26 (0.8) | 50 | |||||
| Hb≥9g/dL | 182 | 27 (1.0) | 46 | 146 | 27 (1.1) | 48 | |||||
|
| |||||||||||
| Minimum | Hb<7g/dL | 284 | 25 (0.8) | <0.001 | 50 | 0.002 | 180 | 23 (0.9) | <0.001 | 54 | <0.001 |
| 7g/dL≤Hb<8g/dL | 234 | 25 (0.9) | 56 | 181 | 24 (1.0) | 57 | |||||
| Hb≥8g/dL | 266 | 29 (0.9) | 41 | 233 | 29 (0.9) | 41 | |||||
|
| |||||||||||
| Maximum | Hb<9g/dL | 212 | 27 (1.0) | 0.27 | 44 | 0.17 | 159 | 26 (1.1) | 0.32 | 47 | 0.36 |
| 9g/dL≤Hb<10g/dL | 278 | 26 (0.8) | 49 | 203 | 26 (0.9) | 49 | |||||
| Hb≥10g/dL | 294 | 25 (0.8) | 52 | 232 | 25 (0.9) | 53 | |||||
|
| |||||||||||
| Admission | Hb<8g/dL | 196 | 26 (1.0) | 0.27 | 47 | 0.37 | 112 | 24(1.2) | 0.23 | 51 | 0.72 |
| 8g/dL≤Hb<10g/dL | 384 | 27 (0.7) | 53 | 309 | 26 (0.8) | 49 | |||||
| Hb≥10g/dL | 204 | 25 (1.0) | 49 | 173 | 25 (1.0) | 52 | |||||
|
| |||||||||||
| Discharge | Hb<8g/dL | 244 | 26 (0.9) | 0.83 | 49 | 0.86 | 160 | 25 (1.1) | 0.59 | 52 | 0.66 |
| 8g/dL≤Hb<9g/dL | 267 | 26 (0.8) | 50 | 292 | 26 (0.8) | 50 | |||||
| Hb≥9g/dL | 273 | 27 (0.9) | 47 | 142 | 26 (1.1) | 50 | |||||
*
Higher fatigue scores equate with lower or less amounts of fatigue
**
P-values for ANOVA
***
P-values for Chi-Squared
SC=Sickle Cell Anemia
GIB=Gastrointestinal Bleeding