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. Author manuscript; available in PMC: 2018 Apr 12.
Published in final edited form as: Acc Chem Res. 2017 Jan 10;50(2):264–272. doi: 10.1021/acs.accounts.6b00472

Figure 3.

Figure 3

Instrumentation for noninvasive near-infrared spectroscopic probing of human fingertip. (A) Fiber probe based portable Raman spectroscopic system developed for transcutaneous glucose monitoring in backscattering configuration. (B) Optical fiber probe showing arrangement of excitation and emission fibers relative to the other optical components. (C) Portable Raman system in transmission mode. (D) CHC used for enhancing light collection, as viewed from the output aperture. (E) Side view of the Raman spectroscopy setup in transmission configuration showing the position of CHC relative to excitation and collection fibers. (F) and (G) Active tissue modulation interface incorporated into measurement device. ((C–E) Reprinted with permission from ref 15. Copyright 2011 AIP Publishing LLC. (F, G) Reprinted with permission from ref 14. Copyright 2011 AIP Publishing LLC.)