Figure 5.

(A) Effects of turbidity on sampling volume as observed from simulations with tissue of different scattering coefficients. (B) Representation of the similar photon-tissue interactions for diffusely reflected and Raman scattered photons of the same wavelength. (C) Illustration of glucose diffusion between the blood and ISF compartments (mass transfer coefficient: k_M) with a smaller amount of cellular uptake (k_U). (D) Physiological lag between the glucose in the two compartments leads to a lack of one-to-one correspondence during rapid changes (rise/fall) in glucose concentrations.