Table 2. Comparison of VcR-CVAD with other intensive induction and consolidation regimens.
PFS | OS | |
---|---|---|
Intensive induction/consolidation regimens | ||
Nordic MCL2 (n=160) R-maxi-CHOP/cytarabine |
6-year 66% | 6-year 70% |
GELA (n=60) R-CHOP/R-DHAP |
Median 7 years | 5-year 75% |
CALGB 59909 (n=78) | 5-year 56% | 5-year 64% |
R-hyper-CVAD (n=97) Single-center |
3-year FFS 64% | 3-year 82% |
R-hyper-CVAD (n=60) GISL |
5-year PFS 61% | 5-year 73% |
R-hyper-CVAD (n=49) SWOG 0213 |
Median 4.8 years | Median 6.8 years |
VcR-CVAD induction maintenance rituximab | ||
WON (n=30) 5 years MR |
6-year PFS 53% 6-year PFS 60% for age <60 |
6-year 70% |
E1405 (n=75) 2 years MR 22 received received ASCT |
3-year PFS 72% 3-year PFS 67% for MR-treated patients |
3-year 88% |