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. 2015 Oct 18;18(6):1479–1487. doi: 10.1093/ntr/ntv231

Table 2.

Effects of Abstinence on Withdrawal Outcomes in Overall Sample

Non-abstinent Abstinent Abstinence-induced change score Abstinence effect
M (SD) Α M (SD) Α M (SD) t d
CO (ppm)a 22.68 (12.09) 5.55 (2.16) −16.98 (11.80) 23.59 −1.44***
Measures
 QSU 1.01 (1.13) 0.95 3.33 (1.07) 0.91 2.32 (1.23) −30.68 1.89***
 MNWS 1.07 (0.94) 0.89 1.84 (1.11) 0.90 0.77 (1.05) −11.89 0.73***
 POMS
  Anger 0.38 (0.61) 0.93 0.63 (0.79) 0.92 0.25 (0.70) −5.78 0.36***
  Anxiety 0.72 (0.71) 0.88 1.15 (0.93) 0.90 0.42 (0.84) −8.06 0.50***
  Confusion 0.78 (0.63) 0.76 0.94 (0.77) 0.80 0.14 (0.71) −2.93 0.20**
  Depression 0.40 (0.61) 0.93 0.52 (0.71) 0.93 0.10 (0.64) −2.54 0.16*
  Fatigue 0.86 (0.90) 0.90 0.85 (0.89) 0.90 −0.03 (0.88) 0.73 −0.03
  Elation 2.01 (0.94) 0.88 1.56 (0.92) 0.87 −0.46 (0.87) 8.49 −0.53***
  Friendliness 2.71 (0.90) 0.92 2.22 (0.97) 0.91 −0.50 (0.81) 9.81 −0.62***
  Vigor 2.20 (0.97) 0.92 1.84 (0.98) 0.91 −0.36 (0.84) 6.77 −0.43***
  NA composite 0.63 (0.61) 0.98 0.82 (0.73) 0.98 0.18 (0.63) −4.39 0.29***
  PA composite 2.31 (0.88) 0.96 1.87 (0.90) 0.96 −0.44 (0.75) 9.28 −0.59***
Behavioral smoking task
 Time delay (min) 39.87 (17.3) 23.56 (23.0) −16.58 (22.7) 11.52 −0.73***
 Cigarettes smoked 1.22 (0.95) 1.53 (0.94) 0.32 (0.93) −5.45 0.34***

CO = carbon monoxide levels (parts per million); QSU = Questionnaire of Smoking Urges (range 0–5); MNWS = Minnesota Nicotine Withdrawal Scale (range 0–5); NA = negative affect; PA = positive affect; POMS = Profile of Mood States (range 0–5); Time Delay (range 0–50 minutes); Cigarettes smoked (range 0–8). Abstinence-Induced Change Score = score in abstinent condition—score in non-abstinent condition.

aNo significant interaction effects were found for CO levels during abstinent sessions and withdrawal outcomes.

*P < .05; **P < .01; ***P < .0001.