Table 1.
Monotherapy |
Additive ciprofloxacin |
Additive levofloxacin |
Additive gentamicin |
Additive tobramycin |
|||||
---|---|---|---|---|---|---|---|---|---|
% | % | p-value | % | p-value | % | p-value | % | p-value | |
Ceftazidime | 75 | 83 | 0.069 | 80 | 0.312 | 86 | 0.011 | 94 | <0.001 |
Cefepime | 55 | 66 | 0.040 | 62 | 0.198 | 71 | 0.002 | 84 | <0.001 |
Aztreonam | 34 | 63 | <0.001 | 56 | <0.001 | 69 | <0.001 | 85 | <0.001 |
Piperacillin-tazobactam | 68 | 76 | 0.125 | 73 | 0.353 | 79 | 0.031 | 89 | <0.001 |
Meropenem | 66 | 75 | 0.082 | 72 | 0.253 | 78 | 0.013 | 88 | <0.001 |
Imipenem | 74 | 83 | 0.039 | 83 | 0.029 | 87 | 0.003 | 93 | 0.039 |
Includes P. aeruginosa isolates recovered from blood, bone, lower respiratory tract, pleural fluid, cerebrospinal fluid, or peritoneal fluid cultures. The majority of isolates, 117 (65%), was cultured from respiratory tract specimens; while 32 (18%), 13 (7%), 13 (7%) and 4 (2%) isolates were collected from blood, bone, peritoneal fluid and pleural fluid specimens, respectively.