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. 2018 Apr 12;13(4):e0195133. doi: 10.1371/journal.pone.0195133

Table 3. Changes in measurements of leg length and skull circumference, from baseline to follow-up, by baseline cognitive status (data pooled across sites).

Change in leg length from baseline to follow-up Change in skull circumference from baseline to follow-up
N Change score (95% CI) n Change score (95% CI)
1. Cognitively normal 6555 -0.85 (-0.99 to -0.71) 6760 -0.20 (-0.23 to -0.16)
2. CIND1 366 -1.31 (-1.87 to -0.75) 375 -0.08 (-0.23 to +0.07)
3. Dementia 442 -2.67 (-3.18 to -2.17) 480 -0.33 (-0.45 to -0.20)
All 7383 -0.99 (-1.12 to -0.85) 7615 -0.20 (-0.23 to -0.17)
Overall effect of baseline cognitive status F = 21.1, 2 df, p<0.001 F = 6.6, 2 df, p = 0.03
Scheffe test p-value for group comparison p-value for group comparison
3 versus 1 p<0.001 p = 0.13
3 versus 2 p = 0.004 p = 0.04
2 versus 1 p = 0.34 p = 0.30

1. Cognitive Impairment, No Dementia