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Neutralization data were analyzed by nonlinear regression analysis and the Ab concentrations (μg/ml) at which 50% of virus infectivity was inhibited, were calculated.
| sCD4 | sCD4D1D2-Igαtp | |||
|---|---|---|---|---|
| WT | D368R | WT | D368R | |
| HIV-1NL4-3 | 0.56 | >50 | 0.03 | >50 |
| HIV-1JR-FL | 3.43 | >50 | 0.06 | >50 |
| HIV-1BG505 | 1.26 | >50 | 0.03 | >50 |
