Table 2. Univariate Cox proportional hazard analysis of morphologic and kinetic features on MR imaging with survival outcomes.
| Variables | No. of patients (recurrence) | Hazard ratio | 95% CI | P value | |
|---|---|---|---|---|---|
| No (n = 269) | Yes (n = 32) | ||||
| Mass shape | |||||
| Oval | 40 (14.9%) | 5 (15.6%) | Reference | ||
| Round | 27 (10.0%) | 3 (9.4%) | 0.926 | 0.221, 3.875 | 0.916 |
| Irregular | 202 (75.1%) | 24 (75.0%) | 1.020 | 0.389, 2.673 | 0.968 |
| Mass margin | |||||
| Circumscribed | 25 (9.3%) | 3 (9.4%) | Reference | ||
| Not circumscribed | 244 (90.7%) | 29 (90.6%) | 1.072 | 0.327, 3.520 | 0.909 |
| Mass internal enhancement | |||||
| Homogeneous | 32 (11.9%) | 2 (6.2%) | Reference | ||
| Heterogeneous | 204 (75.8%) | 22 (68.8%) | 1.829 | 0.430, 7.779 | 0.414 |
| Rim enhancement | 33 (123%) | 8 (25.0%) | 4.004 | 0.850, 18.858 | 0.079 |
| Peak signal intensity (%)* | 252.13 (77–986) | 310.19(132–559) | 1.004 | 1.002, 1.006 | 0.001 |
| Early phase enhancement § | |||||
| Medium (%) | 7.96 | 4.00 | 0.980 | 0.948, 1.013 | 0.234 |
| Rapid (%) | 92.08 | 96.03 | 1.020 | 0.987, 1.054 | 0.236 |
| Delayed phase enhancement § | |||||
| Persistent (%) | 21.22 | 19.3 | 0.997 | 0.982, 1.013 | 0.732 |
| Plateau (%) | 40.69 | 41.56 | 1.001 | 0.983, 1.021 | 0.886 |
| Washout (%) | 38.08 | 39.19 | 1.001 | 0.989, 1.014 | 0.834 |
| Kinetic curve presented by CAD | |||||
| Type 1 (delayed persistent enhancement pattern) | 2 (0.7%) | 0 (0%) | Reference | ||
| Type 2 (delayed plateau enhancement pattern) | 13 (4.8%) | 2 (6.3%) | 4072785.2191 | 0, Inf | 0.997 |
| Type 3 (delayed washout enhancement pattern) | 254 (94.4%) | 30 (93.7%) | 3274787.6777 | 0, Inf | 0.997 |
* Numbers represent the mean values with ranges
§ Numbers represent percentages
CI = confidence interval