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. 2018 Apr 12;13(4):e0195756. doi: 10.1371/journal.pone.0195756

Table 3. Multivariate Cox proportional hazard analysis of clinicopathological variables and MR imaging kinetic parameters with survival outcomes.

Variable Disease-free survival
P value Hazard ratio 95% CI
Peak enhancement 0.013 1.004 1.001, 1.006
T stage
    1 Reference
    2 0.220 1.669 0.737, 3.779
    3 0.215 3.046 0.524, 17.698
    4 0.998 0.000 0.000, ∞
N stage
    0 Reference
    1 0.591 1.267 0.534, 3.004
    2 0.836 0.851 0.185, 3.914
    3 0.081 3.040 0.872, 10.598
Histologic grade
    1 Reference
    2 0.131 3.227 0.704, 14.784
    3 0.176 3.162 0.596, 16.775
Molecular subtype
    Luminal Reference
    HER2-enriched 0.306 3.538 0.314, 39.828
    Triple-negative 0.004 21.060 2.675, 165.780
Adjuvant endocrine therapy
    No 0.263 3.282 0.409, 26.305
    Yes Reference

CI = confidence interval, HER2 = human epidermal growth factor receptor 2