Table 4. Underlying malignancies present in patients with diagnostic features of a DIC.
Primary diagnosis | Staging (Solid organ malignancies) |
World Health organisation subtyping (Haematological malignancies) |
HIV status | Total | ||
---|---|---|---|---|---|---|
Number of patients | ||||||
Negative | Positive | Unknown | ||||
Haematological Malignancies | ||||||
Myelodysplastic syndrome | Myelodysplastic syndrome with excess blasts | 2 | 2 | |||
Acute myeloid leukaemia (AML) | AML with recurrent translocation t(15;17) n = 5 AML with recurrent translocation t(8;21) n = 3 AML NOS, Acute monoblastic n = 1 AML not otherwise specified n = 6 |
4 | 7 | 4 | 15 | |
Chronic Myeloid leukaemia | CML with BCR-ABL1 | - | - | 2 | 2 | |
B-cell Acute Lymphoblastic leukaemia (ALL) | B-cell ALL, not otherwise specified n = 2 | 1 | - | 1 | 2 | |
Acute leukaemia | Not subtyped | 2 | - | 1 | 3 | |
Diffuse Large | Gastric (n = 1), Plasmablastic (n = 1), NOS (n = 1) | - | 2 | 1 | 3 | |
B-cell lymphoma | ||||||
B-cell Lymphoproliferative disorder | Not subtyped | - | 1 | - | 1 | |
Hairy cell leukaemia | Hairy cell leukaemia | 1 | - | 1 | 2 | |
Castleman’s Disease | Castleman’s Disease | 1 | - | - | 1 | |
Monoclonal gammopathy of uncertain significance | 1 | - | - | 1 | ||
Hodgkin Lymphoma | Classical (n = 1), Nodular sclerosing HL (n = 1) HL NOS (n = 1) |
- | 3 | - | 3 | |
Plasma cell myeloma | 1 | 1 | - | 2 | ||
Solid Organ Malignancies | ||||||
Adenocarcinoma | ||||||
Breast Ductal | Stage 4 | - | - | 1 | 1 | |
Ovarian | Stage 4 | - | 1 | 1 | 2 | |
Prostatic | Stage 4 | 1 | - | 1 | 2 | |
Squamous carcinoma | ||||||
Cervical | Stage 1 (1) Stage 2b (1) Stage 4 (3) |
1 | 3 | 1 | 5 | |
Oesophagus | Stage 4 | - | 1 | - | 1 | |
No identifiable primary | Stage 4 | - | - | 2 | 2 | |
Sarcoma | ||||||
Kaposi Sarcoma | Stage 4 | - | 1 | - | 1 |