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. 2018 Apr 12;13(4):e0195793. doi: 10.1371/journal.pone.0195793

Table 4. Underlying malignancies present in patients with diagnostic features of a DIC.

Primary diagnosis Staging
(Solid organ malignancies)
World Health organisation subtyping
(Haematological malignancies)
HIV status Total
Number of patients
Negative Positive Unknown
Haematological Malignancies
Myelodysplastic syndrome Myelodysplastic syndrome with excess blasts 2 2
Acute myeloid leukaemia (AML) AML with recurrent translocation t(15;17) n = 5
AML with recurrent translocation t(8;21) n = 3
AML NOS, Acute monoblastic n = 1
AML not otherwise specified n = 6
4 7 4 15
Chronic Myeloid leukaemia CML with BCR-ABL1 - - 2 2
B-cell Acute Lymphoblastic leukaemia (ALL) B-cell ALL, not otherwise specified n = 2 1 - 1 2
Acute leukaemia Not subtyped 2 - 1 3
Diffuse Large Gastric (n = 1), Plasmablastic (n = 1), NOS (n = 1) - 2 1 3
B-cell lymphoma
B-cell Lymphoproliferative disorder Not subtyped - 1 - 1
Hairy cell leukaemia Hairy cell leukaemia 1 - 1 2
Castleman’s Disease Castleman’s Disease 1 - - 1
Monoclonal gammopathy of uncertain significance 1 - - 1
Hodgkin Lymphoma Classical (n = 1), Nodular sclerosing HL (n = 1)
HL NOS (n = 1)
- 3 - 3
Plasma cell myeloma 1 1 - 2
Solid Organ Malignancies
Adenocarcinoma
Breast Ductal Stage 4 - - 1 1
Ovarian Stage 4 - 1 1 2
Prostatic Stage 4 1 - 1 2
Squamous carcinoma
Cervical Stage 1 (1)
Stage 2b (1)
Stage 4 (3)
1 3 1 5
Oesophagus Stage 4 - 1 - 1
No identifiable primary Stage 4 - - 2 2
Sarcoma
Kaposi Sarcoma Stage 4 - 1 - 1