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. 2018 Apr 12;13(4):e0195765. doi: 10.1371/journal.pone.0195765

Fig 4. Changes in endothelial tight junctions are observed in multiple regions of the brain following BCAS.

Fig 4

A) Representative images of claudin-5 staining (red) within the cortex, hippocampus and striatum of sham or BCAS-treated (14 days) mice. Scale bar = 100 um. Inset images are a magnified portion to show detail. Scale bar = 300 um. B) Quantification of claudin-5-positive pixels. N = 4–6 C) Quantification of occludin gene expression within the cortex and striatum of sham or BCAS treated (14 day) mice. N = 3 *p < 0.05, **p < 0.01.