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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Oral Oncol. 2017 Dec 23;77:83–89. doi: 10.1016/j.oraloncology.2017.12.003

Table 3.

Patient characteristics of CD8 and CD4 cohorts

CD8 Cohort CD4 Cohort

Negative Positive Chi-Squared Negative Positive Chi-Squared

Gender Male 56 (82%) 73 (84%) 0.80 64 (83%) 50 (83%) 0.97
Female 12 (18%) 14 (16%) 13 (17%) 10 (17%)

Subsite Supraglottic 31 (46%) 32 (37%) 0.52 36 (47%) 20 (33%) 0.32
Glottic 36 (53%) 54 (62%) 39 (51%) 39 (65%)
Subglottic 0 (0%) 0 (0%) 1 (1%) 0 (0%)
Unknown 1 (1%) 1 (1%) 1 (1%) 1 (2%)

Initial stage I–II 34 (50%) 49 (56%) 0.12 46 (54%) 31 (53%) 0.99
III–IV 32 (47%) 27 (31%) 34 (40%) 23 (40%)
Unknown 2 (3%) 11 (13%) 5 (6%) 4 (7%)

Initial T T1–2 37 (54%) 53 (61%) 0.09 49 (58%) 35 (60%) 0.68
T3–4 29 (43%) 23 (26%) 31 (36%) 19 (33%)
Unknown 2 (3%) 11 (13%) 5 (6%) 4 (7%)

Initial N N0 51 (75%) 66 (76%) 0.19 63 (74%) 46 (79%) 0.28
N+ 15 (22%) 11 (13%) 18 (21%) 8 (14%)
Unknown 2 (3%) 10 (11%) 4 (5%) 4 (7%)

Recurrent stage I–II 22 (32%) 26 (30%) 0.74 28 (33%) 20 (34%) 0.85
III–IV 46 (68%) 61 70%) 57 (67%) 38 (66%)

Recurrent T TI–2 26 (38%) 29 (33%) 0.53 30 (35%) 24 (41%) 0.46
T3–4 42 (62%) 58 (66%) 55 (65%) 34 (59%)

Recurrent N N0 49 (72%) 63 (72%) 0.96 60 (71%) 46 (79%) 0.24
N+ 19 (28%) 24 (28%) 25 (29%) 12 (21%)

Smoker Yes 64 (94%) 86 (99%) 0.10 74 (96%) 59 (98%) 0.44
No 4 (6%) 1 (1%) 3 (4%) 1 (2%)

Alcohol Yes 43 (63%) 62 (71%) 0.07 52 (68%) 42 (70%) 0.70
No 24 (35%) 19 (22%) 20 (26%) 16 (27%)
Unknown 1 (1%) 6 (7%) 5 (6%) 2 (3%)