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. Author manuscript; available in PMC: 2018 Apr 12.
Published in final edited form as: J Biomed Mater Res A. 2016 May 18;104(7):1581–1590. doi: 10.1002/jbm.a.35769

FIGURE 6.

FIGURE 6

Masson’s Trichrome (A, B) indicates the presence of a chronic inflammatory response (red color) around both stable and failed alginate microbeads with islets and the presence of collagen for a small subset of alginate microbeads without islets. CCR7 stain indicates the presence of inflammatory macrophages (M1) in stable and failed alginate microbeads (C,D) while CD163 pro-healing macrophage phenotype (M2) was not observed in the groups with islets (E), the presence of pro-healing macrophage (CD163+) is observed in stable and failed alginate microbeads without islets (F). Arrows indicate macrophage presence.