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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Hypertension. 2018 Mar 26;71(5):877–885. doi: 10.1161/HYPERTENSIONAHA.117.10560

Figure 3. Restoration of serum Klotho levels inhibited MCP-1 and ICAM-1 expressionin SAMP1 mice.

Figure 3

(A) IHC staining against MCP-1 and ICAM-1 (brown) on the aortic valves of AKR/J and SAMP1 mice treated with AAV.GFP or AAV.SKL. (B) Quantification of MCP-1 and ICAM-1 expression on the leaflets (N=4). Data=means±SEM. **p<0.01, ***p<0.001 vs. AKR/J; + p<0.05, ++ p<0.01 vs. SAMP1+GFP.