Table 2.

Effects of Sub-acute Nicotine Administration on Creatinine Clearance (mL/min) of Wistar Rats.

Creatinine Clearance × 10−3 (mL/min)
GROUPS (n = 5)	Male	Female
[1] Control	4.67 ± 0.66	6.28 ± 0.37
[2] 1 mg/kg	7.38 ± 0.53a, e	9.45 ± 0.49e, b
[3] 2 mg/kg	7.66 ± 0.40a, e	14.29 ± 0.62e, f, c
[4] 4 mg/kg	3.41 ± 0.38f, g	4.61 ± 0.34f, g, d

Each value represents mean ± standard error of mean at p < 0.05.

^asignificantly different from Male control group.

^bsignificantly different from Male group 2.

^csignificantly different from Male group 3.

^dsignificantly different from Male group 4.

^esignificantly different from control.

^fsignificantly different from group 2 of same sex.

^gsignificantly different from group 3 of same sex.