Table 3.

Effects of Sub-acute Nicotine Administration on some Electrolyte Concentrations in the Urine and Plasma of Wistar Rats.

Na+ Concentration (mmol/L)	Plasma Level		Urine Level
GROUPS (n = 5)	Male	Female	Male	Female
[1] Control	135.80 ± 2.08	130.00 ± 1.67	100.60 ± 4.43	70.40 ± 2.36a
[2] 1 mg/kg	129.60 ± 1.36	128.20 ± 2.33	126.40 ± 4.60e	72.80 ± 2.08b
[3] 2 mg/kg	133.80 ± 2.40	132.60 ± 1.40	174.40 ± 3.67e, f	92.80 ± 5.16e, f, c
[4] 4 mg/kg	133.80 ± 1.39	128.20 ± 1.28d	120.80 ± 7.52g	76.60 ± 6.17d
K+ Concentration (mmol/L)
[1] Control	4.20 ± 0.06	3.68 ± 0.12a	129.80 ± 7.43	160.80 ± 4.32a
[2] 1 mg/kg	3.54 ± 0.10e	3.26 ± 0.07e, b	132.60 ± 4.16	227.60 ± 7.33e, b
[3] 2 mg/kg	3.72 ± 0.05e	3.16 ± 0.06e, c	228.60 ± 7.31e, f	185.20 ± 7.79f
[4] 4 mg/kg	3.32 ± 0.08e, g	3.22 ± 0.10e	157.20 ± 9.71g	176.00 ± 6.33f
HCO3− Concentration (mmol/L)
[1] Control	20.80 ± 0.49	21.20 ± 0.49
[2] 1 mg/kg	19.60 ± 0.75	22.40 ± 0.75b
[3] 2 mg/kg	21.60 ± 0.75	20.80 ± 0.49
[4] 4 mg/kg	22.00 ± 0.63	21.20 ± 0.80

Each value represents mean ± standard error of mean at p < 0.05.

^asignificantly different from Male control group.

^bsignificantly different from Male group 2.

^csignificantly different from Male group 3.

^dsignificantly different from Male group 4.

^esignificantly different from control.

^fsignificantly different from group 2 of same sex.

^gsignificantly different from group 3 of same sex.