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. 2018 Apr 12;8:5891. doi: 10.1038/s41598-018-23699-3

Table 4.

Seed-based functional connectivity differences between PIs and GSs.

Seed point Brain regions of peak coordinates R/L BA Voxel volume (mm3) t-score of peak voxel MNI coordinates
X, Y, Z
R_middle temporal gyrus Middle temporal gyrus, inferior temporal gyrus L 20,21 7155 4.9792 −66 −39 −12
Inferior parietal lobule L 7, 39, 40 7803 5.1241 −45 −57 45
L_middle temporal gyrus Middle frontal gyrus, inferior frontal gyrus L 9, 44, 45 18657 −5.204 −51 12 30
R_insula Insula, Postcentral Gyrus L 3, 13 8181 −4.6019 −42 −18 21
L_superior frontal gyrus Precuneus L 7 11259 −5.3114 −3 −60 42

Notes: Statistical threshold was set at voxel threshold of p < 0.01 and cluster threshold of p < 0.01with GRF correction.

Abbreviations: PIs, patients with primary insomnia; GSs, good sleepers; R, right; L, left; BA, Brodmann’s area; MNI, montreal neurological institute; GRF, Gaussian random field.