Table 1.
G-CSF mobilization and coronary stenosis.
| Control (normal saline, 2 mL/d, n = 6) |
Low-dose (G-CSF, 2.5 μg/kg/d, n = 6) |
Middle-dose (G-CSF, 5 μg/kg/d n = 6) |
High-dose (G-CSF, 10 μg/kg/d, n = 6) |
|
|---|---|---|---|---|
| Distal segments of ameroid in LCX | ||||
| 4 weeks after modeling | ||||
| Stenosis, % | 97.2 ± 3.2 | 96.8 ± 5.0 | 96.6 ± 3.8 | 95.9 ± 3.7 |
| 8 weeks after modeling | ||||
| Stenosis, % | 98.8 ± 1.2 | 96.3 ± 2.1 | 87.8 ± 3.6*#†‡ | 92.3 ± 4.5*#† |
| Proximal segments of ameroid in LCX | ||||
| Before modeling | ||||
| Diameter of referring segment, mm | 2.19 ± 0.06 | 2.18 ± 0.06 | 2.22 ± 0.05 | 2.20 ± 0.04 |
| Diameter of ameroid constrictor, mm | 2.20 ± 0.04 | 2.16 ± 0.08 | 2.25 ± 0.08 | 2.18 ± 0.06 |
| 4 weeks after modeling | ||||
| Diameter of referring segment, mm | 2.18 ± 0.07 | 2.18 ± 0.04 | 2.21 ± 0.05 | 2.21 ± 0.06 |
| Minimum diameter, mm | 1.49 ± 0.18 | 1.46 ± 0.20 | 1.47 ± 0.12 | 1.50 ± 0.14 |
| Stenosis, % | 32 ± 5 | 33 ± 6 | 34 ± 5 | 32 ± 7 |
| 8 weeks after modeling | ||||
| Diameter of referring segment, mm | 2.19 ± 0.05 | 2.18 ± 0.07 | 2.21 ± 0.06 | 2.20 ± 0.07 |
| Minimum diameter, mm | 1.03 ± 0.14* | 1.17 ± 0.10* | 1.32 ± 0.12*#†‡ | 1.19 ± 0.15* |
| Stenosis, % | 52 ± 8* | 46 ± 6* | 41 ± 7*#†‡ | 47 ± 6* |
LCX, left circumflex artery.
*P < 0.05 compared with 4 weeks after modeling; #P < 0.05 compared with control group; †P < 0.05 compared with low dose G-CSF therapy group; ‡P < 0.05 compared with high dose G-CSF therapy group.