Table 1.
With bacteremia (n = 42) | Without bacteremia (n = 38) | p-Valued | |
---|---|---|---|
Age (years)a | 72 (16–96) | 60 (20–88) | 0.011 |
Sex (female)b | 21 (50%) | 22 (58%) | 0.479 |
Clinical findings at hospitalizationb | |||
Temperature (°C) | 38.8 (36.9–41.4) | 38.6 (36.6–41.5) | 0.780 |
Heart rate (/min) | 108 (67–140) | 112 (75–136) | 0.900 |
Respiratory frequency (/min) | 24 (15–60) | 25 (11–53) | 0.552 |
Systolic BP (mmHg) | 120 (65–191) | 126 (86–160) | 0.338 |
Organ failureb,c | |||
Total SOFA ≥2 | 36 (85%) | 16 (42%) | <0.001 |
Any failure SOFA ≥2 | 28 (67%) | 10 (26%) | 0.010 |
Respiratory failure | 17 (40%) | 10 (26%) | 0.181 |
Hypotension | 9 (21%) | 3 (8%) | 0.090 |
Bleeding disorder | 5 (12%) | 1 (3%) | 0.107 |
Renal failure | 7 (17%) | 3 (8%) | 0.236 |
Liver failure | 2 (5%) | 1 (3%) | 0.616 |
CNS failure | 3 (7%) | 2 (5%) | 0.729 |
Infection siteb | 0.003 | ||
Urinary tract | 20 (48%) | 17 (45%) | |
Respiratory | 5 (12%) | 13 (34%) | |
Abdominal | 3 (7%) | 0 | |
Soft tissue | 4 (10%) | 8 (21%) | |
CNS | 4 (10%) | 0 | |
Endocarditis | 6 (14%) | 0 | |
Bacteriab | 0.044 | ||
Gram-negative | 25 (60%) | 12 (32%) | |
Gram-positive | 15 (36%) | 23 (61%) | |
Mixed Gram-pos./neg. | 2 (5%) | 3 (8%) | |
Microbe not sensitive to initial treatment | 3 (7%) | 1 (3%) | 0.342 |
Hospitalization atb | 0.103 | ||
HDU | 23 (55%) | 16 (42%) | |
Medical ward | 13 (31%) | 20 (53%) | |
ICU | 6 (14%) | 2 (5%) | |
Hospitalization (days)b | 7.5 (2–55) | 7 (2–50) | 0.399 |
Mortalityb | 1 (2%) | 3 (7%) | 0.259 |
Routine biochemistrya | |||
Hgb (g/dL) | 12.5 (8.7–15.4) | 13.0 (9.2–17.5) | 0.429 |
WBC (109/L) | 13.6 (2.0–27.9) | 14.2 (4.9–46.6) | 0.776 |
Neutrophils (109/L) | 12.1 (1.6–24.3) | 12.1 (4.1–41.1) | 0.866 |
CRP (mg/L) | 175 (3–457) | 158 (7–538) | 0.071 |
Creatinine (μmol/L) | 108 (48–706) | 70 (27–475) | 0.001 |
aMedian (min–max), Mann–Whitney U test.
bN(%), χ2 test.
cDefined as increase in sequential (sepsis-related) organ failure assessment score ≥2, sepsis induced (pre-existing, stable organ failure not included).
dSignificant values are displayed in bold.